Desloratadine/Pseudoephedrine (By mouth)
des-lor-A-ta-deen, soo-doe-e-FED-rin SUL-fate
Treats symptoms of seasonal allergies. This medicine contains an antihistamine and a decongestant.
Drug classes
Antihistamine, Less-Sedating/Decongestant Combination (About this – PubMed Health)
Uses
Uses of This Medicine
Desloratadine and pseudoephedrine is a combination of two medicines used to treat nasal congestion (stuffy nose), sneezing, and runny nose caused by hay fever.
Desloratadine works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.
The pseudoephedrine causes narrowing of blood vessels. This leads to clearing of nasal congestion, but it may also cause an increase in blood pressure in patients who have high blood pressure.
This medicine is available only with your doctor’s prescription.
Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .
Other uses (PubMed Health)
How To Use
24 Hour Tablet, 12 Hour Tablet
Your doctor will tell you how much medicine to use. Do not use more than directed.
Swallow the extended-release tablet whole. Do not crush, break, or chew it.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine if you have used an MAO inhibitor in the past 14 days.
Do not use other antihistamine or decongestant medicines with this medicine, including ones you can buy without a prescription.
Some medicines can affect how this medicine works. Tell your doctor if you are also using any of the following:
Digitalis Reserpine Medicine to lower blood pressureWhen Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to desloratadine, pseudoephedrine, or loratadine, or if you have narrow-angle glaucoma, severe heart disease, severe high blood pressure, or problems urinating.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, high blood pressure, heart disease, glaucoma, thyroid problems, or prostate problems.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Fast, pounding, or uneven heartbeat
Lightheadedness, dizziness, fainting
Severe nervousness or restlessness, tremors, seizures
If you notice these less serious side effects, talk with your doctor:
Trouble sleeping
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
CLARINEX-D 12 HOUR, Clarinex-D, Clarinex-D 24HR
There may be other brand names for this medicine.