Amiloride/Hydrochlorothiazide (By mouth)
a-MIL-oh-ride hye-droe-KLOR-ide, hye-droe-klor-oh-THYE-a-zide
Diuretic, Potassium Sparing/Thiazide Combination (About this – PubMed Health)
Uses of This Medicine
Amiloride and hydrochlorothiazide combination is used alone or with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .
Amiloride and hydrochlorothiazide are both diuretic medicines (water pills). They reduce the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure. Amiloride keeps your body from losing too much potassium when urine flow is increased .
This medicine is available only with your doctor’s prescription .
Other uses (PubMed Health)
How To Use
Your doctor will tell you how much of this medicine to take and how often. Do not take more medicine or take it more often than your doctor tells you to.
It is best to take this medicine with food or milk.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines and foods can affect how this medicine works. Tell your doctor if you are taking any of the following:Cyclosporine, cholestyramine, colestipol, digoxin, dofetilide, lithium, tacrolimus Blood pressure medicine (such as benazepril, enalapril, lisinopril, telmisartan, candesartan), insulin or diabetes medicine you take orally, NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, naproxen, celecoxib), or steroid medicine (such as cortisone, methylprednisolone, prednisone)
Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to amiloride, hydrochlorothiazide, or sulfa drugs, you are unable to urinate, or you have kidney disease or high potassium levels (hyperkalemia).
This medicine may make you dizzy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
Tell any doctor or dentist who treats you that you are using this medicine.
If you stop using this medicine, your blood pressure may go up. High blood pressure usually has no symptoms. Even if you feel well, do not stop using the medicine without asking your doctor.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Chest pain (may be related to your disease and not a side effect)
Lightheadedness or fainting
Problems urinating, pain in side or lower back
Skin rash or itching
Unusual bleeding or bruising
If you notice these less serious side effects, talk with your doctor:
Constipation, mild nausea, vomiting, diarrhea, or upset stomach
Problems having sex
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.