Cabazitaxel (By injection)
ka-baz-i-TAX-el
Drug classes
Antineoplastic Agent (About this – PubMed Health)
Uses
Uses of This Medicine
Cabazitaxel injection is given together with a steroid medicine (eg, prednisone) to treat men with metastatic (cancer that has already spread) prostate cancer. It is used in patients who have already been treated with other medicines that did not work well.
Cabazitaxel belongs to the group of medicines called antineoplastics (cancer medicines). It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. Some of these may be serious and must be reported to your doctor.
This medicine is to be given only by or under the immediate supervision of your doctor.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some foods and medicines can affect how cabazitaxel works. Tell your doctor if you are using any of the following:
Atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or voriconazole Blood thinner (including warfarin) NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)When Not To Use
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to cabazitaxel or polysorbate 80 (a preservative).
Warnings
Tell your doctor if you have kidney disease, liver disease, anemia, an infection, or a history of stomach ulcer or bleeding.
This medicine can cause the following problems:
Kidney problems Stomach and bowel problems (such as bleeding, perforation, inflammation, or blockage)This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Constipation, severe nausea, vomiting, diarrhea, or stomach pain
Decrease in how much or how often you urinate, red or dark brown urine
Fever, chills, cough, sore throat, and body aches
Numbness, tingling, or burning pain in your hands, arms, legs, or feet
Swelling in your hands, ankles, feet, or face
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Joint, muscle, or back pain, tiredness
Mild nausea, vomiting, or diarrhea, loss of appetite
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Jevtana
There may be other brand names for this medicine.