Fluconazole (By injection)
floo-KON-a-zole
Prevents and treats fungal infections.
Drug classes
Antifungal (About this – PubMed Health)
Uses
Uses of This Medicine
Fluconazole injection is used to treat serious fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis [inflammation of the lining of the abdomen or stomach], and infections that may occur in different parts of the body), or fungal (cryptococcal) meningitis. This medicine works by killing the fungus or yeast, or preventing its growth.
Fluconazole injection is also used to prevent candidiasis in patients having bone marrow transplants, who receive cancer or radiation treatment.
This medicine is to be given only by or under the direct supervision of a doctor.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not receive this medicine if you are using astemizole, cisapride, erythromycin, pimozide, quinidine, or terfenadine.
Some foods and medicine can affect how fluconazole works. Tell your doctor if you are using cimetidine, midazolam, prednisone, rifabutin, rifampin, theophylline, tofacitinib, triazolam, vitamin A supplements, or voriconazole. Also tell your doctor if you are using any of the following:
A blood thinner (such as warfarin) A diuretic or “water pill” (such as hydrochlorothiazide), or blood pressure medicine (such as amlodipine, felodipine, isradipine, losartan, nifedipine) Birth control pills Cancer medicine (cyclophosphamide, vinblastine, vincristine) Diabetes medicine that you take by mouth (glipizide, glyburide, tolbutamide) Medicine to lower cholesterol (atorvastatin, fluvastatin, simvastatin) Medicine to treat depression (amitriptyline, nortriptyline) Medicine to treat HIV/AIDS (saquinavir, zidovudine) Medicine to treat malaria (halofantrine) Medicine to treat seizures (carbamazepine, phenytoin) Medicine that weakens the immune system (cyclosporine, sirolimus, tacrolimus) Narcotic pain medicine (alfentanil, fentanyl, methadone) Pain or arthritis medicine (aspirin, celecoxib, diclofenac, ibuprofen, naproxen)When Not To Use
This medicine is not right for everyone. You should not receive this medicine if you had an allergic reaction to fluconazole, or if you are pregnant.
Warnings
It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, heart disease, heart rhythm problems (such as QT prolongation), cancer, or HIV/AIDS.
This medicine may cause the following problems:
Liver problems Serious skin reactions Changes in heart rhythm, such as a condition called QT prolongationThis medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
Call your doctor if your symptoms do not improve or if they get worse.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, or red skin rash
Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Fast, pounding, or uneven heartbeat
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Mild nausea, vomiting, stomach pain, or diarrhea
Pain, itching, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Amerinet Choice Fluconazole, Diflucan, Diflucan IV, Novaplus Fluconazole
There may be other brand names for this medicine.