Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (By mouth)
el-vi-TEG-ra-vir, koe-BIK-i-stat, em-trye-SYE-ta-been, ten-OF-oh-vir al-a-FEN-a-mide
Treats HIV infection. HIV causes AIDS. This medicine does not cure HIV or AIDS, but combinations of drugs may slow the progress of the disease.
Drug classes
Anti-Infective Agent, Antiviral, Reverse Transcriptase Inhibitor Combination (About this – PubMed Health)
Uses
Uses of This Medicine
Elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide combination is used to treat human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). This medicine is usually given to patients who have yet not received any medicine for HIV infection.
Elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide combination will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease from occurring. This medicine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have other problems usually related to AIDS or HIV disease.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Tablet
Your doctor will tell you how much medicine to use. Do not use more than directed.
Do not stop using this medicine without checking first with your doctor. If you stop the medicine even for a short time, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.
It is best to take this medicine with food or milk.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep the bottle tightly closed. Keep the medicine in the original bottle.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine together with alfuzosin, carbamazepine, cisapride, dihydroergotamine, ergotamine, lovastatin, methylergonovine, oral midazolam, phenobarbital, phenytoin, pimozide, rifampin, sildenafil for pulmonary hypertension, simvastatin, triazolam, or St John’s wort.
Some medicines can affect how this medicine works. Tell your doctor if you are using any of the following:
Atorvastatin, bosentan, buspirone, colchicine, cyclosporine, dexamethasone, fluticasone, rifabutin, rifapentine, salmeterol, sildenafil, sirolimus, tacrolimus, tadalafil, vardenafil, zolpidem Birth control pills Blood pressure medicine Blood thinner (including warfarin) Medicine for heart rhythm problems Medicine to treat an infection Medicine to treat depression, seizures, or mental health problems NSAID pain or arthritis medicine (including aspirin, diclofenac, ibuprofen, naproxen)There are many other drugs that can interact with this medicine. Make sure your doctor knows about all other medicines you are using.
If you take an antacid, take it 2 hours before or after you take this medicine.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to elvitegravir, cobicistat, emtricitabine, or tenofovir alafenamide.
Warnings
Tell your doctor if you are pregnant, or if you have kidney problems, liver disease (including hepatitis B), or bone problems (such as osteoporosis).
Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.
This medicine may cause the following problems:
Lactic acidosis Severe liver problems Worsening of hepatitis B infection Kidney problems Lower bone mineral densityYour immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.
This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Change in how much or how often you urinate, cloudy urine
Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Fast breathing, trouble breathing, nausea and vomiting, lightheadedness, severe weakness, tiredness, or confusion
If you notice these less serious side effects, talk with your doctor:
Diarrhea, nausea
Weight gain around your neck, upper back, breast, or waist, moon-shaped face
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Genvoya
There may be other brand names for this medicine.