Norfloxacin (By mouth)
Treats infections. This medicine is a quinolone antibiotic.
Antibiotic (About this – PubMed Health)
Uses of This Medicine
Norfloxacin belongs to the class of medicines known as quinolone antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Take this medicine as directed, and take it at the same time each day.
Take this medicine at least 1 hour before or 2 hours after you eat a meal or use dairy products such as milk, cheese, cream, or yogurt. Take the medicine only with water. Do not take it with milk or with any juice that has calcium added to it.
Drink extra fluids so you will urinate more often and help prevent kidney problems.
Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines and foods can affect how norfloxacin works. Tell your doctor if you are using cisapride, clozapine, cyclosporine, erythromycin, nitrofurantoin, probenecid, ropinirole, tacrine, theophylline, tizanidine, a steroid medicine (such as hydrocortisone, methylprednisolone, prednisone), a blood thinner (such as warfarin), a diabetes medicine (such as glyburide), medicine for depression, medicine for mental illness, NSAID pain medicine (such as aspirin, celecoxib, diclofenac, ibuprofen, naproxen), or medicine for heart rhythm problems (such as amiodarone, procainamide, quinidine, sotalol).
Some minerals and medicines can keep your body from absorbing this medicine. You may need to take norfloxacin at least 2 hours before or 2 hours after you take these medicines. These include magnesium, aluminum, zinc, iron, sucralfate, and didanosine. Ask your pharmacist for more information.
When Not To Use
This medicine is not right for everyone. Do not use if you had an allergic reaction to norfloxacin or similar medicines, or if you had tendon problems after using a quinolone antibiotic.
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, heart disease, heart rhythm problems (such as QT prolongation or a slow heartbeat), myasthenia gravis, G6PD deficiency, or a history of seizures, epilepsy, head injury, or stroke. Tell your doctor if you have ever had tendon or joint problems, including rheumatoid arthritis, or if you have received a transplant.
This medicine may cause the following problems:Heart rhythm changes Nerve damage in the arms or legs Severe diarrhea Tendinitis or tendon rupture (may happen after treatment ends)
This medicine may make you dizzy or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
Call your doctor if your symptoms do not improve or if they get worse.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Change in how much or how often you urinate
Diarrhea that may contain blood
Fast, slow, or uneven heartbeat
Numbness, tingling, weakness, or burning pain in your hands, arms, legs, or feet
Seizures, severe headache, unusual thoughts or behaviors, trouble sleeping, confusion
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Mild diarrhea or nausea
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.