Epinephrine (By injection)
Treats severe allergic reactions (including anaphylaxis) in an emergency situation.
Anaphylaxis Agent, Anesthetic Adjunct, Bronchodilator, Vasopressor (About this – PubMed Health)
Uses of This Medicine
Epinephrine injection is used for emergency treatment of severe allergic reactions (including anaphylaxis) to insect bites or stings, medicines, foods, or other substances. It is also used to treat anaphylaxis caused by unknown substances or triggered by exercise.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Your doctor should teach you how and when to inject this medicine. Each injection kit contains a single-use dose of medicine prescribed for you.
Give yourself a shot right away if you start to have a severe allergic reaction.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
This medicine might come with an autoinjector trainer so you can practice giving the medicine before you have an actual allergic reaction. The autoinjector trainer is gray (for EpiPen® or EpiPen Jr®) or beige (for Adrenaclick®) and does not contain any medicine or needle.
Do not remove the blue safety release (EpiPen® or EpiPen Jr®) or the gray end caps (Adrenaclick®) on the autoinjector until you are ready to use it. Do not put your thumb, fingers, or hand over the orange (EpiPen® or EpiPen Jr®) or red tip (Adrenaclick®).
You may need to use more than one injection if your allergic reaction does not get better after the first shot. Your doctor will give you additional doses if you need more than 2 injections.
You may inject the medicine through your clothing, if you need to.
Some liquid will remain in the autoinjector after the medicine has been injected. This medicine cannot be reused. Give your used autoinjector to your healthcare provider when you seek medical care.
Carry this medicine with you at all times for emergency use in case you have a severe allergic reaction.
Make sure family members or other people you are with know how to inject the medicine in case you are not able to do it yourself.
Check your injection kits regularly to make sure the liquid has not changed color. You should not use the autoinjector if the liquid has changed color, or if there are solids in the liquid. You should not use the autoinjector if the expiration date has passed.
Store the injection kit at room temperature, away from heat, moisture, and direct light. Do not store the medicine in the refrigerator or freezer, or inside a car.
Keep the autoinjector in its case or carrier tube to protect it from damage. This tube is not waterproof. If you accidentally drop it, check for damage or leaks.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some foods and medicines can affect how epinephrine works. Tell your doctor if you are using digoxin, levothyroxine, phentolamine, certain allergy medicines (such as chlorpheniramine, diphenhydramine, tripelennamine), a beta blocker medicine (such as propranolol), a heart rhythm medicine, a diuretic (water pill), an MAO inhibitor (MAOI), medicine for depression, or ergot medicines.
When Not To Use
A severe allergic reaction can be life-threatening, so there is no reason this medicine should not be used.
A severe allergic reaction is a medical emergency. Go to an emergency room as soon as possible, even if you feel better after you use this medicine.
Do not inject this medicine into your hands or feet. Go to the emergency room right away if you accidently inject epinephrine into any part of your body other than your thigh. Epinephrine reduces blood flow, and this could damage areas that have small blood vessels, such as hands and feet.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Fast, pounding, or uneven heartbeat
If you notice these less serious side effects, talk with your doctor:
Feeling anxious, nervous, scared, or weak
Headache or dizziness
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Adrenaclick, Adrenalin, Adrenalin Chloride, Auvi-Q, EPIsnap, EpiPen Auto-Injector, EpiPen Jr Auto-Injector, Epipen, Epipen 2-Pak Auto-Injector, Epipen Jr, Epipen Jr 2-Pak Auto-Injector, NovaPlus Epinephrine, Twinject
There may be other brand names for this medicine.