Ambrisentan (By mouth)
Antihypertensive (About this – PubMed Health)
Uses of This Medicine
Ambrisentan is used to treat symptoms of pulmonary arterial hypertension, which is high blood pressure in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs. When the small blood vessels in the lungs become more resistant to blood flow, the right ventricle must work harder to pump enough blood through the lungs. Ambrisentan works by relaxing these blood vessels and increasing the supply of blood to the lungs, which reduces the workload of the heart.
This medicine is available only with your doctor’s prescription. .
Other uses (PubMed Health)
How To Use
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Swallow the tablet whole. Do not crush, break, or chew it.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Missed dose:Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some foods and medicines can affect how ambrisentan works. Tell your doctor knows if you are using cyclosporine.
When Not To Use
It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. You must use effective birth control to avoid pregnancy while you use this medicine and for at least 1 month after you stop taking the medicine.
Women: You must have a negative pregnancy test before you start using this medicine and every month during your treatment. Tell your doctor right away if you think you have become pregnant.
This medicine may cause the following problems:Fluid retention (edema) Pulmonary edema Anemia
Men: This medicine may affect your ability to father a child by decreasing the amount of sperm made. Talk with your doctor before you use this medicine if you plan to have children.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Chest pain, increased trouble breathing
Fast, pounding heartbeat
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.