Isosorbide Dinitrate (By mouth)
Treats and prevents angina. This medicine is a nitrate.
Antianginal, Coronary Vasodilator (About this – PubMed Health)
Uses of This Medicine
Isosorbide dinitrate belongs to the group of medicines called nitrates. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its work load. When used regularly on a long-term basis, this helps prevent angina attacks from occurring.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Long Acting Capsule, Tablet, Chewable Tablet, Long Acting Tablet
Your doctor will tell you how much medicine to use. Do not use more than directed.
Extended-release tablet or capsule: Swallow the tablet or capsule whole. Do not break, crush, or chew it.
Sublingual tablet: Sit down while you take this medicine. Wet the tablet with water. Place it under your tongue and let it dissolve. Do not chew, crush, or swallow the tablet whole. Do not eat, drink, or smoke while the tablet is dissolving. If your chest pain lasts longer than 5 minutes, put a second tablet under your tongue. If the pain lasts another 5 minutes, use a third tablet. If your pain does not go away after the third dose, call your doctor and have someone take you to a hospital.
Missed dose: If you miss a dose or forget to use your medicine, use it as soon as you can. If your next regular dose is less than 2 hours away, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to isosorbide.
Medicines that treat angina sometimes cause headaches. These headaches are a sign that the medicine is working. Do not stop taking the medicine or change the time you take it to avoid the headaches. Ask your doctor if you can take aspirin or acetaminophen to treat the headache.
This medicine could cause low blood pressure, which may make you feel dizzy or lightheaded. Do not drive or do anything that could be dangerous until you know how this medicine affects you. You may feel lightheaded when standing, so stand up slowly. Drinking alcohol may make these symptoms worse.
Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Blue lips or fingernails, trouble breathing
Increased chest pain, slow heartbeat
Severe or ongoing dizziness, lightheadedness, or fainting
Throbbing or severe headache, confusion, fever, trouble seeing
If you notice these less serious side effects, talk with your doctor:
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Apo-Isdn, Dilatrate-SR, IsoDitrate, Isochron, Isordil, Isordil Titradose
There may be other brand names for this medicine.