Axitinib (By mouth)
Antineoplastic Agent (About this – PubMed Health)
Uses of This Medicine
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. Take each dose 12 hours apart.
Swallow the tablet whole with a glass of water. Do not break, crush, or chew it.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions.
If you vomit after you take the medicine, do not take more. Just take your next dose at the regular time.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some foods and medicines can affect how axitinib works. Tell your doctor if you are using any of the following:Bosentan, dexamethasone, modafinil, nafcillin, nefazodone, St John’s wort HIV/AIDS medicine, such as atazanavir, efavirenz, etravirine, indinavir, nelfinavir, ritonavir, saquinavir Infection medicine, such as clarithromycin, itraconazole, ketoconazole, telithromycin, voriconazole Seizure medicine, such as carbamazepine, phenobarbital, phenytoin Tuberculosis medicine, such as rifabutin, rifampin, rifapentine
Do not eat grapefruit or drink grapefruit juice while you are using this medicine.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to axitinib or you are pregnant.
This medicine may cause the following problems:High blood pressure Bleeding problems or blood clots Heart failure Tears or holes in your stomach or bowel Thyroid changes Reversible posterior leukoencephalopathy syndrome (RPLS)
Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Cancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Fast, slow, or pounding heartbeat
Red or brown urine, bloody or black stools, vomiting blood
Seizure, headache, confusion, trouble seeing
Severe or ongoing stomach pain
Swelling in your hands, ankles, or feet
Unusual bleeding, bruising, tiredness, or weakness
If you notice these less serious side effects, talk with your doctor:
Decreased appetite and weight loss
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.