Methylergonovine (By mouth)
Uterine Stimulant (About this – PubMed Health)
Uses of This Medicine
Methylergonovine is used to prevent and control bleeding from the uterus that can happen after childbirth. It belongs to the class of medicines called ergot alkaloids. This medicine works by acting directly on the smooth muscles of the uterus and prevents bleeding after giving birth.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Your doctor will tell you how much medicine to use. Do not use more than directed. This medicine is usually given for up to 1 week after childbirth, as directed by your doctor.
If a dose is missed:
Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using another ergot medicine (such as ergotamine, Cafergot®, Ergomar®, Wigraine®) or a blood pressure medicine (such as atenolol, metoprolol, propranolol, Bystolic®, Tenormin®).
Make sure your doctor knows if you are also using medicine to treat an infection (such as clarithromycin, clotrimazole, erythromycin, fluconazole, itraconazole, ketoconazole, troleandomycin, voriconazole, Biaxin®, Diflucan®, Ery-tab®, Nizoral®), medicine to treat HIV infection (such as delavirdine, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir, Norvir®, Rescriptor®), or medicine to treat depression (such as fluoxetine, fluvoxamine, nefazodone, Serzone®). Tell your doctor if you are also using rifampicin (Rifadin®, Rimactane®), zileuton (Zyflo®) or medicine to treat severe chest pain or angina (such as nitroglycerin, Nitro-Bid®, Nitrostat®, Transderm-Nitro®).
Do not eat grapefruit or drink grapefruit juice while you are using this medicine.
When Not To Use
You should not use this medicine if you have had an allergic reaction to methylergonovine, or if you have high blood pressure or toxemia. If you are pregnant, you should use this medicine only if you are in labor.
Your unborn baby could be harmed if you use this medicine before you go into labor. This medicine may cause contractions of the uterus and cause you to give birth early.
Do not breastfeed for at least 12 hours after your last dose of this medicine.
This medicine may increase your chance of heart problems or a heart attack. This is more likely if you already have heart disease, if you have diabetes or high cholesterol, or if you smoke or are overweight. Call your doctor right away if you have chest pain or discomfort; nausea or vomiting; pain or discomfort in the arms, jaw, back, or neck; trouble breathing; or sweating.
Your doctor will check your progress closely while you are taking this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Chest pain or discomfort, fast or uneven heartbeat, sweating, trouble breathing, or pain in the arm, back, or jaw
Decrease in how much or how often you urinate
Tingling of the fingers, toes, or feet
If you notice these less serious side effects, talk with your doctor:
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
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There may be other brand names for this medicine.