Muromonab (By injection)
Immunological Agent (About this – PubMed Health)
Uses of This Medicine
When a patient receives an organ transplant, the body’s white blood cells will try to get rid of (reject) the transplanted organ. Muromonab-CD3 works by preventing the white blood cells from doing this.
The effect of muromonab-CD3 on the white blood cells may also reduce the body’s ability to fight infections. Before you begin treatment, you and your doctor should talk about the good this medicine will do as well as the risks of using it.
Muromonab-CD3 is to be administered only by or under the immediate supervision of your doctor.
Other uses (PubMed Health)
How To Use
Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.
A doctor, nurse, or other trained health professional will give you this medicine.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
When Not To Use
You should not receive this medicine if you have had an allergic reaction to muromonab, if you are pregnant or breastfeeding, if you have congestive heart failure, edema (swelling, rapid weight gain), high blood pressure that is not controlled, or if you have a history of seizures.
Make sure your doctor knows if you have had a recent heart attack or blood loss, or if you have a history of heart disease, stroke, blood clots, head injury, infection, chest pain (angina), or lung disease.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Extreme lightheadedness or fainting
Fast or irregular heartbeat
Shortness of breath or trouble swallowing
If you notice these less serious side effects, talk with your doctor:
Sensitivity to light
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Orthoclone OKT 3
There may be other brand names for this medicine.