Liothyronine (By injection)
lye-oh-THYE-roe-neen
Treats severe hypothyroidism (the body does not produce enough thyroid hormone). This medicine is a man-made thyroid hormone.
Drug classes
Diagnostic Agent, Thyroid Function, Thyroid Supplement (About this – PubMed Health)
Uses
Uses of This Medicine
Liothyronine is used to treat myxedema coma or precoma, a very serious complication of hypothyroidism. Hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormone .
Liothyronine injection can be used as a substitute for the oral dose when a rapid effect is needed and when the oral route is not allowed .
This medicine is available only with your doctor’s prescription .
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
Your doctor will switch you to a thyroid medicine given by mouth when your thyroid problem is controlled by this medication. Be sure to follow all your doctor’s instructions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using a blood thinner such as warfarin (Coumadin®). Make sure your doctor knows if you are also using a vasopressor (increases your blood pressure) medicine, such as epinephrine, norepinephrine, Adrenalin®, Levophed®, Sus-Phrine®. Make sure your doctor knows if you are using digoxin (Digitek®, Lanoxin®). Another name for digoxin is digitalis.
Make sure your doctor knows if you are also using insulin or diabetes medicines you take by mouth, such as glyburide, metformin, Actos®, Amaryl®, Avandia®, Glucophage®, Glucotrol®, or Glucovance®.
Make sure your doctor knows if you are also using any estrogens or if you are also using birth control pills containing estrogen. Examples of estrogen medicines include estradiol, estropipate, Activella®, Climara®, Femhrt®, Premarin®, and Vivelle-Dot®. Examples of birth control pills include Apri®, Aviane®, Microgestin®, Mircette®, Necon®, Ortho-Cyclen®, Ortho-Novum®, Ortho Tri-Cyclen®, and Trivora®.
Make sure your doctor knows if you are also using a tricyclic antidepressant medicine. Examples include amitriptyline, doxepin, imipramine, nortriptyline, Elavil®, Pamelor®, or Sinequan®.
Make sure your doctor knows about all other medicines you are using. Certain medicines or foods may change the medical tests used to check your thyroid.
When Not To Use
You should not be given this medicine if you have had an allergic reaction to liothyronine. You should not be given this medicine if you have adrenal gland problems (Addison’s disease, adrenal cortical insufficiency) that have not been treated yet. You should not be given this medicine if you have an overactive thyroid gland (hyperthyroid, Grave’s disease, thyrotoxicosis) that has not be treated yet.
Warnings
Make sure your doctor knows if you are pregnant or breast feeding, or if you have heart, kidney, or liver problems. Make sure your doctor knows if you have diabetes mellitus (sugar diabetes) or diabetes insipidus (water diabetes), or if you have adrenal gland problems (Addison’s disease, adrenal cortical insufficiency).
Make sure your doctor knows if you have any other medical problems. Certain medical problems may change the medical tests used to check your thyroid.
Your doctor will need to check your progress regularly while you are being given this medicine.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Bluish-colored skin
Chest pain.
Shortness of breath or trouble breathing.
Swelling in your hands, ankles, or feet.
Uneven or fast heartbeat.
If you notice these less serious side effects, talk with your doctor:
Light-headedness or dizziness or fainting.
Muscle twitching.
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Triostat
There may be other brand names for this medicine.