Palonosetron (By injection)
Antiemetic (About this – PubMed Health)
Uses of This Medicine
Palonosetron injection is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy). It is also used to prevent nausea and vomiting that may occur after surgery. Palonosetron works by blocking the signals to the brain that cause nausea and vomiting.
This medicine is to be given only by or under the direct supervision of your doctor.
Other uses (PubMed Health)
How To Use
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
This medicine is usually given about 30 minutes before the start of chemotherapy or right before you receive anesthetic medicine for surgery.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines can affect how palonosetron works. Tell your doctor if you are using any of the following:Fentanyl, lithium, tramadol, mirtazapine Medicine to treat depression MAO inhibitor (MAOI)
When Not To Use
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to palonosetron.
Tell your doctor if you are pregnant or breastfeeding, or if you had an allergic reaction to another medicine for nausea or vomiting.
This medicine may cause a serious drug reaction called serotonin syndrome (more likely if used together with certain other medicines).
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Chest pain, fast, slow, pounding, or uneven heartbeat
Lightheadedness, dizziness, fainting
If you notice these less serious side effects, talk with your doctor:
Pain, redness, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.