CIN-3 (Cervical Intraepithelial Neoplasia Grade 3)
Abnormal are found in the innermost lining of the . These abnormal cells may become and spread into nearby normal .
In recent decades various researchers have tried to estimate how likely it is that will develop into . Their findings are summarized in the table below. For example: low-grade or moderate dysplasia (CIN 1 and CIN 2) goes away again without in 45 to 60 out of 100 women, usually within a year. In 10 to 25 out of 100 women it will develop into high-grade dysplasia. This can take several years and is influenced by many factors, such as the type of virus.
Some trials followed what happened in women for up to 18 years. Estimates about how common it is for high-grade (CIN 3) to develop into invasive if left untreated vary greatly: they range from 12 out of 100 women within 10 years, to more than 50 out of 100 women within 30 years.