Romidepsin (By injection)
Antineoplastic Agent (About this – PubMed Health)
Uses of This Medicine
Romidepsin injection is used to treat certain types of cancer of the white blood cells called cutaneous T-cell lymphoma (CTCL) and peripheral T-cell lymphoma (PTCL). This medicine is used in a patient who has already been treated with other medicines.
Romidepsin interferes with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. Some of these may be serious and must be reported to your doctor. Before you begin treatment with romidepsin, you and your doctor should talk about the benefits of this medicine as well as the risks of using it.
This medicine is to be given only by or under the direct supervision of a doctor.
Other uses (PubMed Health)
How To Use
Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
This medicine is usually given on days 1, 8, and 15 of a 28-day cycle of treatment. Each treatment takes about 4 hours.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some foods and medicines can affect how romidepsin works. Tell your doctor if you are using the following:Dexamethasone, nefazodone, St John’s wort A blood thinner (such as warfarin) Medicine for heart rhythm problems Medicine for tuberculosis (rifabutin, rifampin, rifapentine) Medicine to treat HIV or AIDS (atazanavir, indinavir, nelfinavir, ritonavir, saquinavir) Medicine to treat an infection (clarithromycin, itraconazole, ketoconazole, telithromycin, voriconazole) Medicine to treat seizures (carbamazepine, phenobarbital, phenytoin)
When Not To Use
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to romidepsin, or if you are pregnant.
It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
This medicine may cause the following problems:Heart rhythm problems Tumor lysis syndrome
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Infections could be severe or even life-threatening.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Cancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Change in how much or how often you urinate, burning during urination
Chest pain, shortness of breath
Fast, pounding, or uneven heartbeat, dizziness, lightheadedness
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Change or loss of taste
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.