Rufinamide (By mouth)
Treats seizures in patients who have Lennox-Gastaut syndrome.
Anticonvulsant (About this – PubMed Health)
Uses of This Medicine
Rufinamide is used to control seizures (convulsions) that occur with Lennox-Gastaut syndrome (LGS). It works in the brain to prevent seizures. This medicine will not cure LGS and will only control seizures for as long as you continue to take it.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
It is best to take this medicine with food or milk. The tablets may be taken whole, broken in half, or crushed if needed.
Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Shake the bottle well just before you take each dose.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the oral liquid upright. Use the liquid within 90 days after you open the bottle for the first time. Throw away any unused medicine.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines can affect how rufinamide works. Tell your doctor if you are using any of the following:Carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, valproate Birth control pills
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to rufinamide, or if you have familial short QT syndrome.
This medicine may cause the following problems:Changes in heart rhythm Multi-organ hypersensitivity reaction, which can damage organs such as liver, kidneys, or heart
This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely. Your seizures may return or happen more often if you stop this medicine suddenly.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Depression, unusual moods or behavior, thoughts of hurting yourself
Fast, pounding, or uneven heartbeat, fainting
If you notice these less serious side effects, talk with your doctor:
Mild nausea or vomiting
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.