Insulin Aspart/Insulin Degludec (By injection)
IN-su-lin AS-part, ree-KOM-bi-nant, IN-su-lin de-GLOO-dek
Antidiabetic (About this – PubMed Health)
Uses of This Medicine
Insulin aspart is a fast-acting type of insulin. Insulin degludec is a long-acting type of insulin that works slowly, over about 24 hours. Insulin is one of many hormones that help the body turn the food we eat into energy. This is done by using the glucose (sugar) in the blood as quick energy. Also, insulin helps us store energy that we can use later. When you have diabetes mellitus, your body cannot make enough insulin or does not use insulin properly. This causes you to have too much sugar in your blood. Like other types of insulin, insulin aspart and insulin degludec combination is used to keep your blood sugar level close to normal.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin. You will be taught how to give yourself insulin shots. Make sure you understand all instructions. Ask your doctor if you have questions.
Take this medicine with a main meal. You may also use a fast-acting insulin or short-acting insulin with other meals, if needed.
Look at the insulin and make sure it is clear before you use it. Do not mix this medicine with water or other insulin, and do not use in an insulin pump.
You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
Use a new needle and syringe each time you inject your medicine.
Always check the label to make sure you have the correct type of insulin.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: Take your next dose with your next main meal on the same day, and continue with your regular dosing schedule. Do not use extra medicine to make up for a missed dose.
Unopened Ryzodeg® FlexTouch: Store the disposable prefilled pen in the refrigerator until the expiration date on the carton, or at room temperature for up to 28 days. Protect from light. Do not freeze.
Opened Ryzodeg® FlexTouch: Store the disposable prefilled pen at room temperature for up to 28 days. Keep away from direct heat and light. Do not refrigerate.
Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines may affect your blood sugar level, including a diuretic (water pill), birth control pills, corticosteroid (including dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone), phenothiazine medicine (including chlorpromazine, perphenazine, prochlorperazine, promethazine, thioridazine), thyroid medicine, niacin, and isoniazid.
Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.
Limit how much alcohol you drink.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to insulin aspart or insulin degludec.
This medicine may cause the following problems:Low blood sugar Low potassium levels Fluid retention or heart failure (when used together with a thiazolidinedione [TZD] medicine)
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Shaking, trembling, sweating, lightheadedness, hunger, confusion
If you notice these less serious side effects, talk with your doctor:
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.