Isavuconazonium (By injection)
eye-sa-vue-koe-na-ZOE-nee-um SUL-fate
Treats fungal infections.
Drug classes
Antifungal (About this – PubMed Health)
Uses
Uses of This Medicine
Isavuconazonium injection is used to treat serious fungal or yeast infections, such as invasive aspergillosis and invasive mucormycosis. This medicine works by killing the fungus or yeast and preventing its growth.
This medicine is to be given only by or under the direct supervision of your doctor.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine together with carbamazepine, ketoconazole, phenobarbital, rifampin, ritonavir, or St John’s wort.
Some foods and medicines can affect how isavuconazonium works. Tell your doctor if you are using any of the following:
Atorvastatin Bupropion Cyclosporine Digoxin Lopinavir/ritonavir Midazolam Mycophenolate mofetil Sirolimus TacrolimusWhen Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to isavuconazonium.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease or heart rhythm problems (such as familial short QT syndrome). Tell your doctor if you had an allergic reaction to similar medicines (including itraconazole, ketoconazole, voriconazole).
This medicine may cause liver problems.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, red skin rash
Chills, dizziness, trouble breathing
Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Decrease in how much or how often you urinate, difficult or painful urination
Dry mouth, increased thirst, muscle cramps, uneven heartbeat
Lightheadedness, dizziness, or fainting
Numbness or tingling, change in sense of touch
If you notice these less serious side effects, talk with your doctor:
Headache, trouble sleeping
Nausea, vomiting, constipation, diarrhea
Rapid weight gain, swelling in your hands, ankles, or feet
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Cresemba
There may be other brand names for this medicine.