Lidocaine/Prilocaine (On the skin)
Anesthetic Combination, Anesthetic, Local (About this – PubMed Health)
Uses of This Medicine
Lidocaine and prilocaine topical cream is used on the skin or in the genital area to cause numbness or loss of feeling before certain medical procedures. It is used to prevent pain caused by an injection, the drawing of blood from a vein, or minor surgeries such as removing warts. This medicine contains a mixture of two topical local anesthetics (numbing medicines). It deadens the nerve endings in the skin.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Cream, Thin Sheet
A nurse or other trained health professional will give you this medicine. The medicine is usually applied right before the medical procedure in a hospital or clinic.
You may be taught how to apply this medicine to yourself or your child at home before the medical procedure.
Your doctor will tell you how much medicine to use. Do not use more than directed. Do not use it for any other condition without first checking with your doctor. This medicine may cause unwanted effects if too much is used, because more of it is absorbed through the skin.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Apply a thick layer of medicine to the area where numbness is needed. Do not spread the medicine on the skin.
Cover the medicine with a special bandage called an occlusive dressing. This will keep the medicine in place. Your doctor will give you the bandage or tell you what to use.
Seal the edges of the bandage to keep the medicine from leaking. Do not lift the bandage or disturb it. Keeping the medicine tightly covered helps it work properly.
For babies or young children, a second covering may be used to prevent them from touching the medicine.
Keep the bandage in place until you or your child arrive at the hospital or clinic.
Your doctor will remove the bandage and wipe the medicine off the skin before the medical procedure.
How to Store and Dispose of This Medicine:
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using acetaminophen, acetanilid, aniline dyes, benzocaine (Americaine®), chloroquine (Aralen®), dapsone, or naphthalene. Tell your doctor if you are also using nitrofurantoin (Furandantin®), nitroglycerin (Nitrostat®), nitroprusside (Nitropress®), pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital (Luminal®), phenytoin (Dilantin®), primaquine, quinine, or a sulfonamide antibiotic (such as trimethoprim/sulfamethoxazole, Bactrim®).
Tell your doctor if you are also using a medicine to treat an abnormal heart rhythm such as amiodarone (Cordarone®), bretylium (Bretylol®), dofetilide (Tikosyn®), flecainide (Tambocor®), mexiletine (Mexitil®), propafenone (Rythmol®), quinidine (Cardioquin®, Quinaglute®, Quinidex®), sotalol (Betapace®), or tocainide (Tonocard®).
When Not To Use
Make sure your doctor knows if you are pregnant or breastfeeding, or if you or your child have liver disease, heart disease, heart rhythm problems, methemoglobinemia (blood disease), or glucose-6-phosphate dehydrogenase (G6PD) deficiency (blood disease).
Do not use this medicine on a baby younger than 3 months of age unless your child’s doctor tells you to. Young babies may have more unwanted effects if too much is used and absorbed through the skin. If you use this medicine on a baby younger than 3 months of age, blood tests may be needed to check for unwanted effects.
Do not use this medicine to treat a skin problem your doctor has not examined.
During the time that the skin feels numb, serious injury can occur. Be especially careful to avoid injury until the numbness wears off and you or your child have normal feeling in the area. Do not scratch or rub the area, and do not allow very hot or very cold objects to touch it.
Using too much of this medicine or using it on a large area of your skin can cause serious unwanted effects. Remove the cream and contact your doctor right away if you or your child have any of these symptoms: lightheadedness, dizziness, vision problems, an irregular or slow heartbeat, difficulty with breathing, or convulsions.
This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash; itching; hoarseness; trouble with breathing; trouble with swallowing; or any swelling of the hands, face, or mouth after you receive the medicine.
This medicine may cause a rare, but serious blood problem called methemoglobinemia. Remove the cream and call your doctor right away if you or your child develop a blue or bluish purple color on the lips, fingernails, or skin, or have headaches, dizziness, fainting, sleepiness, or trouble with breathing.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Confusion, dizziness, sleepiness, or lightheadedness.
Loss of color in your face or lips.
Skin turns a blue color around your mouth, fingers, or toes.
If you notice these less serious side effects, talk with your doctor:
Mild burning, itching, or rash.
Pale or red skin where the medicine was applied.
Swelling of the skin where the medicine was applied.
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Emla, Relador Pak, Relador Pak Plus
There may be other brand names for this medicine.