Hyaluronidase (By injection)
hye-al-ure-ON-i-dase
Helps your body absorb other medicines. Also helps add fluid to your body when you are dehydrated.
Drug classes
Tissue Permeability Modifier (About this – PubMed Health)
Uses
Uses of This Medicine
Hyaluronidase is a natural substance found in the body, which is collected from either cows or pigs. It is cleaned up to remove animal substances. It may also be produced in a laboratory that recreates it from human albumin sources.
Hyaluronidase injection is a spreading substance. It is used with other medicines given under the skin to improve their uptake by the body. This method of drug delivery is only used when the drug cannot be given by injection into a vein. Hyaluronidase injection is also used to increase absorption of fluids or medicines that are injected into your skin. It also used to help improve absorption of radioactive substances during a procedure called subcutaneous urography.
This medicine is to be given only by or under the direct supervision of a doctor.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
A nurse or other health provider will give you this medicine.
Before your injection, you may be given a skin test to make sure you are not allergic to this medicine.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
When Not To Use
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hyaluronidase.
Warnings
Tell your doctor if you are pregnant or breastfeeding.
This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Rapid weight gain, swelling in your hands, ankles, or feet
If you notice these less serious side effects, talk with your doctor:
Redness, swelling, itching, or pain at the injection site
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Amphadase, HyQvia, Hydase, Hylenex, Vitrase
There may be other brand names for this medicine.