Polymyxin B (By injection)
pol-ee-MIX-in B SUL-fate
Antibiotic (About this – PubMed Health)
Uses of This Medicine
Polymyxin B belongs to the group of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.
This medicine is to be given only by or under the direct supervision of a doctor.
Other uses (PubMed Health)
How To Use
A nurse or other trained health professional will give you this medicine.
Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.
Missed dose: Call your doctor or pharmacist for instructions. This medicine needs to be given on a fixed schedule.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Tell your doctor if you recently had surgery or a procedure that included the use of anesthesia. The muscle relaxers and anesthetics used may interact with polymyxin B.
Tell your doctor if you are taking or have recently taken another antibiotic, such as bacitracin, streptomycin, neomycin, kanamycin, gentamicin, tobramycin, or amikacin. You could have a higher risk of side effects if you take any of these with polymyxin B.
When Not To Use
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to polymyxin.
This medicine may cause the following problems:Kidney problems Nerve problems
This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
Call your doctor if your symptoms do not improve or if they get worse.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Clumsiness, weakness, numbness, tingling feeling
Decrease in how much or how often you urinate, bloody or cloudy urine, trouble urinating
Diarrhea that may contain blood
Dizziness, drowsiness, or irritability
If you notice these less serious side effects, talk with your doctor:
White spots in your mouth or throat, vaginal itching, or unusual vaginal discharge
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Novaplus Polymyxin B Sulfate
There may be other brand names for this medicine.