WEDNESDAY, Sept. 28, 2016 (HealthDay News) — A British study says it provides new evidence that marijuana use may boost the risk that people who struggle with psychosis will relapse.
But critics said the effect seems to be small, and they questioned the validity of the research.
A study co-author stands by the work, however.
“We show that pot use causes an increase in the risk of relapse in psychosis and demonstrate that alternative explanations are unlikely to be true,” said Dr. Sagnik Bhattacharyya, a reader in translational neuroscience and psychiatry at King’s College London.
“It would be appropriate to at least aim for reduction in pot use in patients with psychosis if complete abstinence is not realistic,” Bhattacharyya added.
People suffering from psychosis lose touch with reality and may hallucinate, develop delusions and struggle to think and speak normally. Sometimes psychosis is a symptom of a condition like schizophrenia, bipolar disorder or depression, according to the National Alliance on Mental Illness.
Earlier this year, a British study in the journal BMJ Open linked pot use in psychosis patients to higher levels of hospitalization and less response to medications. But experts said at the time that this could be because psychotic patients turn to marijuana when they’re feeling less stable or because genetics make a person likely to both become psychotic and want to use pot.
In the new study, researchers looked at 220 patients — 90 women and 130 men, aged 18 to 65 — who were diagnosed for the first time with psychosis. Bhattacharyya said his team tried to expand upon the previous research by using statistical techniques to look more closely at the impact of pot.
The researchers found that the risk that patients would relapse was 13 percent higher when they used pot than when they didn’t. And the odds appeared to go up when the patients used more pot. This suggests — but doesn’t prove — that pot use raises the risk of relapse, instead of the other way around, the researchers said.
They added that it’s not clear how pot use might boost the risk of relapse. Nor is it clear whether marijuana may have beneficial effects that aren’t being measured, or if the drug may cause more relapses while making them less severe.
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