Glyburide (By mouth)
GLYE-bure-ide
Treats type 2 diabetes.
Drug classes
Hypoglycemic (About this – PubMed Health)
Uses
Uses of This Medicine
Glyburide is used to treat high blood sugar levels caused by a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream. Chronic high blood sugar can lead to serious health problems in the future.
Proper diet is the first step in managing type 2 diabetes, but often medicines are needed to help your body. Glyburide belongs to a class of medicines called sulfonylureas. It causes your pancreas to release more insulin into the blood stream. This medicine may be used alone or with another oral medicine such as metformin.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Tablet
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Take this medicine with breakfast or your first main meal of the day unless your doctor tells you differently.
Missed dose:Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine together with bosentan.
Some foods and medicines can affect how glyburide works. Tell your doctor if you are using aspirin, chloramphenicol, ciprofloxacin, cyclosporine, disopyramide, fluoxetine, isoniazid, miconazole, niacin, phenytoin, probenecid, warfarin or another blood thinner, an NSAID pain or arthritis medicine, medicine to treat an infection, a sulfa medicine, a phenothiazine medicine, an MAO inhibitor, blood pressure medicines, a diuretic (water pill), a steroid medicine, thyroid medicine, estrogens, or birth control pills.
If you are also taking colesevelam, take it at least 4 hours after you take glyburide.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to glyburide.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel problems, adrenal or pituitary gland problems, or G6PD deficiency. Tell your doctor if you drink alcohol.
This medicine may cause the following problems:
Higher risk of heart or blood vessel problems Low blood sugarYour doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. .
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blurred vision, changes in vision
Fast or pounding heartbeat, lightheadedness, dizziness
Headache or confusion
Sweating, trembling, shakiness, increased hunger
If you notice these less serious side effects, talk with your doctor:
Heartburn, gas, or feeling full
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Diabeta, Euglucon, Glycron, Glynase Pres-Tab, Micronase
There may be other brand names for this medicine.