Spironolactone (By mouth)
Antiandrogen, Cardiovascular Agent (About this – PubMed Health)
Uses of This Medicine
Spironolactone is also used to diagnose and treat hyperaldosteronism, a condition in which the adrenal gland produces too much hormone called aldosterone. This medicine may also be used to treat fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome.
Spironolactone is a potassium-sparing diuretic (water pill). It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. This medicine is also used to treat or prevent hypokalemia (low potassium levels in the blood).
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine together with eplerenone.
Some medicines and foods can affect how spironolactone works. Tell your doctor if you use the following:Cholestyramine, digoxin, heparin, lithium An NSAID pain or arthritis medicine (such as aspirin, celecoxib, diclofenac, ibuprofen, indomethacin, naproxen) A steroid medicine (such as hydrocortisone, methylprednisolone, prednisolone, prednisone)
Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium. You could have high levels of potassium in your blood that would cause serious health problems.
Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to spironolactone, or if you have Addison disease.
This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Do not stop using the medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
Tell any doctor or dentist who treats you that you are using this medicine.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Blood in your stools or dark stools, vomiting blood or material that looks like coffee grounds
Confusion, weakness, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
Lightheadedness, dizziness, drowsiness, fainting
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Breast swelling, enlargement, pain, or tenderness
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.