Laronidase (By injection)
lar-ON-i-dase
Treats mucopolysaccharidosis I (MPS I).
Drug classes
Endocrine-Metabolic Agent, Enzyme Replacement (About this – PubMed Health)
Uses
Uses of This Medicine
Laronidase is used to treat Hurler and Hurler-Schele syndrome forms of mucopolysaccharidosis (MPS I) disease caused by the lack of a certain enzyme called α-L-iduronidasein the body.
Laronidase is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
This medicine is usually given once a week. The medicine is injected slowly, so the needle will remain in place for 3 to 4 hours.
Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
When Not To Use
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to laronidase.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease, lung disease or breathing problems, you use oxygen, or you have an infection or illness.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Chest pain, swelling in your hands, ankles, or feet
Fast, slow, pounding, or uneven heartbeat
Fever, chills, cough, sore throat, runny or stuffy nose
Lightheadedness or fainting
Numbness, tingling, or burning pain in your hands, arms, legs, or feet
Trouble breathing, rapid or shallow breathing
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
Rash or itching
Warmth or redness in your face, neck, or chest
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Aldurazyme
There may be other brand names for this medicine.