Azathioprine (By injection)
Antirheumatic, Cytotoxic (About this – PubMed Health)
Uses of This Medicine
Azathioprine injection is used to prevent rejection of a transplanted kidney. It belongs to the group of medicines known as immunosuppressive agents. Azathioprine will lower the body’s natural immunity in patients who receive transplants to prevent rejection of the new kidney. It is also used to relieve joint pain and swelling for patients with rheumatoid arthritis.
This medicine is to be given only by or under the immediate supervision of your doctor.
Other uses (PubMed Health)
How To Use
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any questions about this, talk to your doctor.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines can affect how azathioprine works. Tell your doctor if you are also using allopurinol, cotrimoxazole, mercaptopurine, mesalamine, olsalazine, ribavirin, sulfasalazine, a blood thinner (such as warfarin), or blood pressure medicines (ACE inhibitors).
When Not To Use
This medicine is not right for everyone. You should not receive this medicine if you had an allergic reaction to azathioprine, or if you are pregnant.
It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
Tell your doctor if you are breastfeeding, or if you have kidney disease, Crohn disease or bowel problems, blood or bone marrow problems (such as anemia, low white blood cells, or low platelets in the blood), or any type of infection.
This medicine may cause the following problems:Higher risk of skin cancer or lymphoma Higher risk of infection, including progressive multifocal leukoencephalopathy (PML) Serious intestinal allergic reactions
Use sunscreen with a sun protection factor (SPF) of at least 15 when you are outdoors. Wear protective clothing and hats, and stay out of direct sunlight between the hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds.
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Lightheadedness or fainting
Sores on the skin
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Joint or muscle pain
Sores or white patches on your lips, mouth, or throat
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.