Esomeprazole (By injection)
es-oh-MEP-ra-zole SOE-dee-um
Treats gastroesophageal reflux disease (GERD). Lowers the risk of bleeding after endoscopy in patients with ulcers. This medicine is a proton pump inhibitor (PPI).
Drug classes
Gastric Acid Secretion Inhibitor (About this – PubMed Health)
Uses
Uses of This Medicine
Esomeprazole injection is used to treat conditions where there is too much acid in the stomach. It is used for the short-term treatment (up to 10 days) of gastroesophageal reflux disease (GERD) with erosive esophagitis in adults and children 1 month of age and older. GERD is a condition where the acid in the stomach washes back up into the esophagus. This medicine is also used to lower risk of rebleeding in patients with acute gastric or duodenal ulcer after endoscopy.
Esomeprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid that is produced by the stomach.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following:
Atazanavir, cilostazol, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John’s wort, tacrolimus, voriconazole Blood thinner (such as clopidogrel or warfarin) Diuretic (water pill) Iron supplementsWhen Not To Use
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to esomeprazole or similar medicines.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease or osteoporosis.
This medicine may cause the following problems:
Kidney problems Broken bones in the hip, wrist, or spine Low magnesium levels in the bloodThis medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, red skin rash
Fast, slow, pounding, or uneven heartbeat
Fever, joint pain, swelling in your body, unusual weight gain, changes in how much or how often you urinate
Seizures, dizziness, muscle spasms, muscle cramps or twitching
Severe diarrhea that does not go away, fever
Stomach pain, nausea, vomiting, weight loss
If you notice these less serious side effects, talk with your doctor:
Gas
Redness, pain, itching, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Nexium I.V.
There may be other brand names for this medicine.