Piperacillin/Tazobactam (By injection)
pi-per-a-SIL-in SOE-dee-um, taz-oh-BAK-tam SOE-dee-um
Treats infections. The medicine contains a penicillin antibiotic.
Drug classes
Antibiotic (About this – PubMed Health)
Uses
Uses of This Medicine
Piperacillin and tazobactam injection is used to treat bacterial infections in many different parts of the body.
Piperacillin and tazobactam combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.
This medicine is to be given only by or under the direct supervision of your doctor.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some foods and medicines can affect how piperacillin/tazobactam works. Tell your doctor if you are using any of the following medicines:
Methotrexate Probenecid Diuretic (water pill) Other medicine to treat an infection (such as tobramycin) Blood thinner (such as warfarin)When Not To Use
This medicine is not right for everyone. You should not receive this medicine if you had an allergic reaction to piperacillin, tazobactam, or similar antibiotic medicines.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, congestive heart failure, or cystic fibrosis. Tell your doctor if you have a history of allergies or are on a low-salt diet.
This medicine may cause the following problems:
Bleeding problems Serious skin reactions Severe diarrheaThis medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop taking this medicine.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Call your doctor if your symptoms do not improve or if they get worse.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, or red skin rash
Diarrhea that may contain blood
Trouble breathing
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Headache, trouble sleeping
Mild diarrhea, constipation, nausea
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Novaplus Piperacillin Sodium-Tazobactam Sodium, Novaplus Zosyn, PremierPro Rx Piperacillin and Tazobactam, Zosyn
There may be other brand names for this medicine.
