Pemetrexed (By injection)
Antineoplastic Agent (About this – PubMed Health)
Uses of This Medicine
Pemetrexed injection treats lung cancer and belongs to the group of medicines called antineoplastics. It is used together with cisplatin (a cancer medicine) to treat a type of cancer called malignant pleural mesothelioma (MPM). This cancer affects the inside lining of the chest cavity. Pemetrexed injection may also be used alone or together with cisplatin to treat a type of lung cancer called nonsquamous non-small cell lung cancer.
To lower your chances of side effects with pemetrexed, you must also take folic acid and vitamin B12 prior to and during your treatment. Your doctor will prescribe a medicine called a corticosteroid (cortisone medicine) to take for 3 days during your treatment. Corticosteroid medicines lower your chances of getting skin reactions with pemetrexed.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
The medicine is usually given on day 1 of a treatment cycle. This treatment cycle is often 21 days, but it might be longer.vitamin B12 injection in the week before your first treatment, and then about every 9 weeks while you receive treatment. Your doctor will give you a steroid medicine to take the day before, the day of, and the day after each injection.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
If a dose is missed:
This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using probenecid (Benemid®) or pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, indomethacin, meloxicam, nabumetone, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®).
When Not To Use
You should not receive this medicine if you have had an allergic reaction to pemetrexed, or if you are pregnant.
It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Cancer medicines can cause diarrhea, nausea, or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Decrease in how much or how often you urinate
Dry mouth or skin, increased thirst, lightheadedness, dizziness, fainting
Lower back or side pain
Red or dark brown urine
Unusual bleeding, bruising, weakness
If you notice these less serious side effects, talk with your doctor:
Constipation, nausea, or vomiting
Sores or white patches on your lips, mouth, or throat
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.