Prasugrel (By mouth)
PRA-soo-grel
Prevents blood clots, which can lead to heart attack, in patients who need to have percutaneous coronary intervention (PCI).
Drug classes
Platelet Aggregation Inhibitor (About this – PubMed Health)
Uses
Uses of This Medicine
Prasugrel is used to prevent strokes, heart attacks, or other serious problems with your heart or blood vessels. It is given to patients before they have a heart procedure called percutaneous coronary intervention (PCI).
A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot. Prasugrel reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping or sticking together. Prasugrel may also increase the chance for serious bleeding in some people.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Tablet
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Your doctor may tell you to take aspirin with this medicine.
Do not break the tablet.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep the tablets in the original container.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines and foods can affect how prasugrel works. Tell your doctor if you are also using any of the following:
NSAID pain or arthritis medicine, such as aspirin, diclofenac, ibuprofen, naproxen, celecoxib Blood thinner, such as warfarin Other medicine to treat or prevent blood clotsWhen Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to prasugrel or have a history of stroke.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have any bleeding problems. Also tell your doctor if you have kidney disease, liver disease, or stomach ulcer, or if you are allergic to clopidogrel or ticlopidine.
This medicine increases your risk of bleeding. Tell your doctor about all recent surgeries and injuries and if you have ever had bleeding in your stomach or intestines. Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
This medicine may cause thrombotic thrombocytopenic purpura (TTP), a serious blood clot problem.
Do not stop taking this medicine without checking with your doctor first. Your risk for blood clots increases if you stop this medicine suddenly.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Bleeding that will not stop
Blood in your urine or stools
Change in how much or how often you urinate
Chest pain
Nosebleeds
Pinpoint red or purple spots on the skin
Trouble breathing, tiredness, fever, yellow skin or eyes, fast or pounding heartbeat, headache
Unusual bleeding or bruising
Vomiting of blood or material that looks like coffee grounds
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Effient
There may be other brand names for this medicine.