Chlorothiazide (By injection)

klor-oh-THYE-a-zide

Treats edema. This medicine is a diuretic (water pill) and an antihypertensive.

Drug classes

Cardiovascular Agent (About this – PubMed Health)

Uses

Uses of This Medicine

Chlorothiazide is used to treat fluid retention (edema) that is caused by congestive heart failure, severe liver disease (cirrhosis), kidney disease, or from treatment with a steroid or hormone medicine.

Chlorothiazide is a thiazide diuretic. It reduces the amount of water in the body by increasing the flow of urine, which helps reduce fluid retention (edema).

This medicine is available only with your doctor’s prescription.

Other uses (PubMed Health)

How To Use

Injectable

Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Many other drugs can interact with chlorothiazide. Make sure your doctor knows about all other medicines you are taking, including those you get without a prescription.

Tell your doctor if you are taking any of the following:

Blood pressure medicine Insulin, or diabetes medicine that you take by mouth Lithium NSAIDs, such as aspirin, diclofenac, ibuprofen, naproxen, celecoxib Steroid medicine, such as hydrocortisone, methylprednisolone, prednisone

Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

When Not To Use

This medicine is not right for everyone. Do not receive it if you had an allergic reaction to chlorothiazide or to sulfa drugs, or if you cannot urinate.

Warnings

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, asthma, lupus, or gout. Tell your doctor if you recently had surgery.

This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Possible side effects

Summary More details

Call your doctor right away if you notice any of these side effects:

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Blistering, peeling, red skin rash

Blood in your urine, or change in how much or how often you urinate

Confusion, weakness, and muscle twitching

Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

Dry mouth, increased thirst, muscle cramps

Lightheadedness or fainting

Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

Pain, burning, itching, or irritation where the needle is placed

Patchy hair loss

Headache or joint pain

Numbness in your feet, legs, or arms

Problems with sex (in men)

If you notice other side effects that you think are caused by this medicine, tell your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

More side effects of this drug

Brand names include

Diuril Sodium, PremierPro RX Chlorothiazide Sodium, Sodium Diuril

There may be other brand names for this medicine.