Esterified Estrogens/Methyltestosterone (By mouth)
es-TER-i-fide ES-troe-jenz, meth-il-tes-TOS-ter-one
Treats symptoms of menopause, such as hot flashes. Estrogens are female hormones and methyltestosterone is a male hormone.
Drug classes
Estrogen/Androgen Combination (About this – PubMed Health)
Uses
Uses of This Medicine
Esterified estrogens and methyltestosterone combination is used to treat the symptoms of menopause in patients who did not get relief after being treated with estrogens alone. These symptoms may include a feeling of heat, sweating, and warmth in the face, neck, or chest (“hot flashes”); and dryness, burning, and itching in the vagina.
Esterified estrogens are a man-made mixture of estrogens. Estrogen is a hormone that is produced by the body in greater amounts in females. It is necessary for normal sexual development of the female and for regulation of the menstrual cycle during the childbearing years. Methyltestosterone is a man-made form of testosterone, a hormone that is produced by the body in greater amounts in males and small amounts in females. Menopause symptoms occur when the hormone balance changes in the female body. This combination of hormones will relieve the symptoms of menopause by adding more hormones to the body.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Tablet
Your doctor will tell you how much medicine to take and how often.
If a dose is missed:
Take the missed dose as soon as possible.
Skip the missed dose if it is almost time for your next regular dose.
You should not use two doses at the same time.
How to Store and Dispose of This Medicine:
Store at room temperature; protect from heat, moisture, and direct light.
Keep all medicine out of the reach of children.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Tell your doctor if you are taking blood thinners (such as Coumadin®).
When Not To Use
You should not use this medicine if you have ever had an allergic reaction to estrogens or androgens. You should not use if you are pregnant (or think you may be pregnant), if you are breastfeeding, or if you have any unusual vaginal bleeding. You should not use if you have severe liver disease, or have heart or circulation problems, including a history of blood clots, or breast cancer.
Warnings
Check with your doctor before taking this medicine if you have asthma, diabetes, epilepsy, migraine headaches, heart disease, kidney disease, depressed mood, or liver disease.
You should see your doctor regularly (usually every 6 months to 1 year) while taking this medicine.
Unless you have had a hysterectomy (uterus removed), check with your doctor about whether you should also take progesterone.
Large doses of this medicine taken over long periods of time may increase the risk of some kinds of cancer. Talk to your doctor about this risk.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Severe stomach pain or swelling
Heavy vaginal bleeding
Chest or leg (calf) pain
Shortness of breath
Breast lumps
If you notice these less serious side effects, talk with your doctor:
Mild nausea or vomiting
Bloated feeling
Mild dizziness
Headache
Changes in sexual desire
Swollen or tender breasts
Fluid retention and weight gain
Contact lens discomfort
Depressed mood
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Covaryx, Covaryx HS, EEMT, EEMT HS, Essian, Estratest, Menogen, Syntest D.S., Syntest DS, Syntest H.S.
There may be other brand names for this medicine.
