Posaconazole (By injection)
poe-sa-KON-a-zole
Treats or prevents fungus infections.
Drug classes
Antifungal (About this – PubMed Health)
Uses
Uses of This Medicine
Posaconazole injection is used to prevent certain fungus (yeast) infections in patients who have a weakened immune system (eg, hematopoietic stem cell transplant or HSCT recipients, or patients with blood cancers).
This medicine is to be given only by or under the direct supervision of a doctor.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine together with atorvastatin, lovastatin, pimozide, quinidine, simvastatin, sirolimus, ergotamine, or dihydroergotamine.
Some medicines can affect how posaconazole works. Tell your doctor if you are using cimetidine, cyclosporine, digoxin, esomeprazole, glipizide, metoclopramide, phenytoin, rifabutin, tacrolimus, vinblastine, vincristine, medicine for HIV/AIDS (atazanavir, efavirenz, fosamprenavir, ritonavir), a sedative medicine (alprazolam, midazolam, triazolam), or blood pressure medicine (diltiazem, felodipine, nicardipine, nifedipine, verapamil).
When Not To Use
This medicine is not right for everyone. You should not receive this medicine if you had an allergic reaction to posaconazole or similar medicines.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or heart rhythm problems (such as QT prolongation).
This medicine may cause the following problems:
Heart rhythm problems Liver problemsYour doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Fast, slow, pounding, or uneven heartbeat
Severe diarrhea or vomiting
Swelling in your arms or legs
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Fever or chills
Mild diarrhea, constipation, nausea, vomiting, stomach pain
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Noxafil
There may be other brand names for this medicine.