Samarium Sm 153 Lexidronam Pentasodium (By injection)
sa-MAR-ee-um Sm 153 lex-ID-roe-nam
Reduces pain caused by bone cancer.
Drug classes
Radiopharmaceutical, Antineoplastic (About this – PubMed Health)
Uses
Uses of This Medicine
Samarium Sm 153 lexidronam is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of the body’s organs or to treat certain diseases.
Samarium Sm 153 lexidronam is used to help relieve the bone pain that may occur with certain kinds of cancer. The radioactive samarium is taken up in the bone cancer area and gives off radiation that helps provide relief of pain.
Samarium Sm 153 lexidronam is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine or radiation oncology.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your exact dose, and how often this medicine should be given.
This medicine is given through a needle placed in one of your veins.
You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine. Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
If a dose is missed:
This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are receiving medicines to treat cancer such as chemotherapy, or if you have had radiation treatment.
When Not To Use
You should not receive this medicine if you have had an allergic reaction to samarium Sm 153 lexidronam or similar phosphonate compounds. You should not receive this medicine if you are pregnant.
Warnings
This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant.
Make sure your doctor knows if you are breast feeding.
Make sure your doctor knows if you have had congestive heart failure, kidney disease, or a bleeding disorder.
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Bloody urine.
Chest pain, uneven heartbeat.
Fever, chills, cough, sore throat, or body aches.
Light-headedness or fainting.
Muscle cramps, or bone problems.
Numbness or weakness in your arm or leg, or on one side of your body.
Unusual bleeding, bruising, or weakness.
If you notice these less serious side effects, talk with your doctor:
Cough.
Dizziness.
Nausea, vomiting, stomach pain, or diarrhea.
Pale lips.
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Quadramet
There may be other brand names for this medicine.