Colesevelam (By mouth)
koe-le-SEV-e-lam hye-droe-KLOR-ide
Lowers cholesterol levels and treats type 2 diabetes.
Drug classes
Antihyperlipidemic (About this – PubMed Health)
Uses
Uses of This Medicine
Colesevelam is used together with proper diet to lower high cholesterol levels in the blood. This may help prevent medical problems caused by cholesterol clogging the blood vessels. This medicine is also used to treat high blood sugar levels for patients with type 2 diabetes.
Colesevelam works by attaching to food substances in the intestine. This medicine is not absorbed from the intestine, so these substances pass out of the body without being absorbed.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Liquid, Tablet
Your doctor will tell you how much medicine to use. Do not use more than directed.
Take this medicine with a meal and liquid.
Powder: Mix the powder with one-half to one cup of water, fruit juice, or a diet soft drink. Stir well and drink right away.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines can affect how colesevelam works. Tell your doctor if you are taking any of the following. He may tell you to take your other medicine at least 4 hours before you take colesevelam.
A blood thinner, such as warfarin Birth control pills Cyclosporine Glyburide Levothyroxine Metformin PhenytoinWhen Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to colesevelam. Do not use it if you have a history of bowel blockage, severe hypertriglyceridemia, or pancreatitis caused by hypertriglyceridemia.
Warnings
Tell your doctor if you are pregnant or breastfeeding.
Tell your doctor if you have trouble swallowing, ongoing problems with constipation, phenylketonuria (PKU), a history of vitamin A, D, E, or K deficiency, or you had stomach or bowel surgery.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Fever, chills, cough, sore throat, and body aches
Headache, dizziness, or blurred vision
Sudden and severe stomach pain, nausea, vomiting, fever, and lightheadedness
Trouble swallowing
Weakness, confusion, drowsiness, increased hunger, fast heartbeat, or shakiness
If you notice these less serious side effects, talk with your doctor:
Constipation or nausea
Loss of strength
Runny or stuffy nose
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Welchol
There may be other brand names for this medicine.