Amitriptyline (By mouth)
Treats depression. This medicine is a TCA.
Antidepressant, Urinary Enuresis Agent (About this – PubMed Health)
Uses of This Medicine
Amitriptyline is used to treat symptoms of depression. It works on the central nervous system (CNS) to increase levels of certain chemicals in the brain. This medicine is a tricyclic antidepressant (TCA).
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use this medicine with cisapride. Do not use this medicine and an MAO inhibitor (MAOI) within 14 days of each other.
Some medicines and foods can affect how amitriptyline works. Tell your doctor if you are using cimetidine, disulfiram, or guanethidine. Tell your doctor if you are using other medicine for depression (such as fluoxetine, paroxetine, sertraline), a phenothiazine medicine (such as promethazine, chlorpromazine), medicine for heart rhythm problems (such as flecainide, propafenone, quinidine), or thyroid medicine.
When Not To Use
This medicine is not right for everyone. Do not use if you had an allergic reaction to amitriptyline.
For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
This medicine may cause the following problems:Heart rhythm problems High or low blood sugar levels
This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Chest pain, trouble breathing
Fast, pounding, or uneven heartbeat
Feeling more excited or energetic than usual, racing thoughts, trouble sleeping
Lightheadedness, dizziness, or fainting
Thoughts of hurting yourself or others, unusual behavior
Unusual bleeding or bruising
If you notice these less serious side effects, talk with your doctor:
Change in how much or how often you urinate
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Elavil, Sentravil PM-25, Vanatrip
There may be other brand names for this medicine.