Maprotiline (By mouth)
Antidepressant (About this – PubMed Health)
Uses of This Medicine
Maprotiline is used to relieve mental depression, including anxiety that sometimes occurs with depression.
Maprotiline is available only with your doctor’s prescription.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, maprotiline is used in certain patients with the following medical condition:
Other uses (PubMed Health)
How To Use
Your doctor will tell you how much to take and how often. Take this medicine exactly as ordered by your doctor.
Do not stop taking maprotiline suddenly without first asking your doctor.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
If a dose is missed:
Take the missed dose as soon as possible.
If it is almost time for your next regular dose, wait until then to take the medicine and skip the missed dose.
You should not use two doses at the same time.
How to Store and Dispose of This Medicine:
Store at room temperature in a closed container, away from heat, moisture, and direct light.
Keep all medicine out of the reach of children.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not drink alcohol while taking this medicine.
Make sure your doctor knows if you are taking other medicines that could make you drowsy, such as sleeping pills, tranquilizers, cold and allergy medicines, and pain killers.
When Not To Use
You should not use this medicine if you have ever had an allergic reaction to maprotiline. Check with your doctor before taking this medicine if you have seizures (epilepsy), if you have recently had a heart attack, or if you are taking monoamine oxidase (MAO) inhibitors such as Marplan®, Parnate, Nardil®.
If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
Make sure your doctor knows if you have had heart problems, overactive thyroid, glaucoma, or if you have trouble urinating.
For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
Maprotiline may make you drowsy or dizzy. Be careful driving a car or operating machinery.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Irregular or rapid heartbeat
If you notice these less serious side effects, talk with your doctor:
Drowsiness, dizziness, or tiredness
Changes in vision such as trouble focusing
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.