Idursulfase (By injection)
eye-dur-SUL-fase
Improves walking ability in people with Hunter syndrome.
Drug classes
Enzyme Replacement (About this – PubMed Health)
Uses
Uses of This Medicine
Idursulfase injection is used to treat Hunter syndrome (Mucopolysaccharidosis II, MPS II), a rare condition that is most often seen in males. Hunter syndrome is an inherited disease in which the breakdown of a certain chemical in the body (mucopolysaccharide) is defective due to the lack or absence of an enzyme called iduronate-2-sulfatase.
Idursulfase improves signs and symptoms in patients, especially walking capacity, by replacing the missing enzyme in Hunter syndrome.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
When Not To Use
This medicine is not right for everyone. Tell your doctor if you had an allergic reaction to idursulfase, because you might need other medicine or a different schedule to prevent a reaction.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease, lung disease, or breathing problems.
This medicine may cause a serious allergic reaction up to 24 hours after you receive it.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Fast, pounding, or uneven heartbeat
If you notice these less serious side effects, talk with your doctor:
Mild skin itching
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Elaprase
There may be other brand names for this medicine.
