Naloxone (Into the nose)
nal-OX-one
Treats opioid overdose in an emergency situation. Must be given as soon as possible.
Drug classes
Antidote (About this – PubMed Health)
Uses
Uses of This Medicine
Naloxone nasal spray is used for emergency treatment of an opioid overdose or a possible overdose. It will temporarily reverse the effects of an opioid medicine. Some signs and symptoms of an opioid emergency are breathing problems (which can range from slow or shallow breathing to no breathing), extreme sleepiness, slow heartbeat, or not being able to respond, a very small (pinpoint) pupil in a person who is difficult to awaken.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Spray
Your doctor will tell you how much medicine to use. Do not use more than directed.
This medicine must be given to you (the patient) by someone else. Talk with people close to you so they know what to do in case of an emergency.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
This medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.
To use:
Each nasal spray contains only one dose of naloxone. Do not prime or test the nasal spray. Hold the nasal spray with your thumb on the bottom of the plunger and your first and middle fingers on either side of the nozzle. Lay the patient on his or her back. Support the patient’s neck with your hand and let the head tilt back. Gently insert the tip of the nozzle into one nostril, until your fingers on either side of the nozzle are against the bottom of the patient’s nose. Press the plunger firmly to give the dose. Remove the nasal spray from the patient’s nose. Move the patient on his or her side (recovery position). Get emergency medical help right away. Watch the patient closely. If needed, you may give more doses every 2 to 3 minutes until the patient responds. Use a new nasal spray for each dose and spray the medicine into the other nostril each time.Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.
Ask your pharmacist about the best way to dispose of medicine that you do not use.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to naloxone.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have heart or blood vessel disease.
This medicine should be given right away after a suspected or known overdose of an opioid (narcotic) medicine. This will help prevent serious breathing problems and severe sleepiness that can lead to nerve damage or death. .
The effects of the opioid medicine may last longer than the effects of the naloxone. This means the breathing problems and sleepiness could come back. Always call for emergency help after the first dose of naloxone.
This medicine could cause withdrawal symptoms from the opioid medicine.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Crying more than the usual (in babies)
Diarrhea, nausea, vomiting, stomach cramps
Fast, pounding, or uneven heartbeat
Fever, runny nose, sneezing, sweating, yawning
Ongoing trouble breathing
Seizure, shaking, or feeling restless, nervous, or irritable
If you notice these less serious side effects, talk with your doctor:
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Narcan
There may be other brand names for this medicine.
