Micromedex Detailed Drug Information for the Consumer [Internet]. Truven Health Analytics; 1974-2016.

Oxycodone (Oral route)

ox-i-KOE-done hye-droe-KLOR-ide

Brand Name(s)

In the US: Dazidox, Eth-Oxydose, Oxaydo, OxyCONTIN, OxyCONTIN CR, Oxydose, Oxyfast, Oxy IR, Roxicodone, Roxicodone Intensol

In Canada: APO-Oxycodone CR, CO oxyCODONE CR, oxyCODONE, Oxy-IR, OxyNEO, pms-oxyCODONE

Dosage forms

Tablet, Extended Release Tablet Capsule Solution

Classifications

Therapeutic: Analgesic; Chemical: Oxycodone

Warning

Oral route (Tablet, Extended Release)

Addiction, abuse, and misuse, leading to overdose and death has been reported. Before prescribing, assess the patient’s risk and watch for signs of the development of these behaviors. Serious and fatal respiratory depression may occur. Monitor for respiratory depression, especially when beginning treatment or increasing dose. Advise patients to swallow tablets whole to avoid overdose. Accidental ingestion can result in a fatal overdose, especially in children. Prolonged use in pregnancy may lead to life-threatening neonatal withdrawal syndrome. If oxycodone hydrochloride must be used during pregnancy, advise the patient of the risk and ensure that treatment will be available to the infant. Initiation of CYP3A4 inhibitors or discontinuation of CYP3A4 inducers can cause a fatal oxycodone hydrochloride overdose .

Oral route (Solution)

Use caution when prescribing and administering oxycodone oral solution as dosing errors due to mg and mL could result in accidental overdose and death. Ensure the proper dose is indicated and dispensed. Oxycodone oral solution should be kept out of the reach of children. Seek emergency help immediately if accidental ingestion occurs .

Uses of This Medicine

Oxycodone is used to relieve moderate to severe pain. It belongs to the group of medicines called narcotic analgesics (pain medicines). Oxycodone acts on the central nervous system (CNS) to relieve pain.

Oxycodone extended-release tablets should not be used if you need pain medicine for just a short time, such as when recovering from surgery. Do not use this medicine to relieve mild pain, or in situations when non-narcotic medication is effective. This medicine should not be used to treat pain that you only have once in a while or “as needed”.

When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only with your doctor’s prescription.

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: