C1 Esterase Inhibitor Recombinant (By injection)

C1 ES-ter-ase in-HIB-i-ter ree-KOM-bi-nant

Treats hereditary angioedema (HAE) attacks.

Drug classes

Immune Modulator (About this – PubMed Health)

Uses

Uses of This Medicine

C1 esterase inhibitor recombinant is used to treat hereditary angioedema (HAE) in adults and teenagers. HAE is a rare disease that causes swelling of the face, hands, feet, throat, stomach, bowels, or sexual organs. People who have HAE have low levels of C1 esterase inhibitor in their body, and this medicine increases the amount of C1 esterase inhibitor in the body.

This medicine is available only with your doctor’s prescription.

Other uses (PubMed Health)

How To Use

Injectable

Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

A nurse or other health provider will give you this medicine.

You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

Use a new needle and syringe each time you inject your medicine.

The mixed liquid should be clear and colorless. Do not use this medicine if it is cloudy, discolored, or contains solid particles.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Store the powder vial in the refrigerator or at room temperature. Keep the medicine in the original carton until you are ready to use it. Do not freeze.

Use the mixed medicine right away, or within 8 hours if it has been stored in the refrigerator.

Throw away the vial after use, even if there is medicine left in it.

Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Some medicines can affect how C1 esterase recombinant works. Tell your doctor if you are using birth control pills.

When Not To Use

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to C1 esterase inhibitor, rabbits, or rabbit-derived products.

Warnings

Tell your doctor if you are pregnant or breastfeeding, or if you have atherosclerosis or a history of blood clots.

Carry this medicine with you at all times. An HAE attack may become life-threatening and requires immediate medical attention. Check with your doctor right away, or go to an emergency room as soon as possible, if your symptoms do not go away after you use this medicine.

This medicine may increase your risk for blood clots.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible side effects

Summary More details

Call your doctor right away if you notice any of these side effects:

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Chest pain or tightness, trouble breathing, or coughing up blood

Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking

Pain in your lower leg (calf)

If you notice these less serious side effects, talk with your doctor:

Mild headache

Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

More side effects of this drug

Brand names include

Ruconest

There may be other brand names for this medicine.