Amifostine (By injection)
Cytoprotective Agent (About this – PubMed Health)
Uses of This Medicine
Amifostine is to be given only by or under the immediate supervision of your doctor.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in the product labeling, amifostine is used in certain patients with the following medical conditions:
Mucositis in patients receiving radiation therapy or radiation combined with chemotherapy
Other uses (PubMed Health)
How To Use
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines can affect how amifostine works. Tell your doctor if you are taking any of the following:A diuretic (water pill), such as furosemide, hydrochlorothiazide (HCTZ), torsemide Medicines for high blood pressure, such as amlodipine, atenolol, clonidine, lisinopril, metoprolol, olmesartan
When Not To Use
This medicine is not right for everyone. Do not receive it if you had an allergic reaction to amifostine.
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, heart disease, heart failure, or heart rhythm problems. Tell your doctor if you have a history of low blood pressure, stroke, or transient ischemic attacks (TIA).
Drink extra fluids during the 24 hours before you receive this medicine.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Chest pain, or fast, slow, or uneven heartbeat
Fever or chills
Severe nausea or vomiting
Sores or white patches on your lips, mouth, or throat
Sudden dizziness or lightheadedness
Swelling in your hands, ankles, or feet
Unusual tiredness or weakness
If you notice these less serious side effects, talk with your doctor:
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
Unusual drowsiness or sleepiness
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.