Factor IX Complex, Recombinant (By injection)

FAK-tor NINE

Prevents and controls bleeding in patients with hemophilia B.

Drug classes

Antihemophilic Agent, Hemostatic (About this – PubMed Health)

Uses

Uses of This Medicine

Factor IX is a protein produced naturally in the body. It helps the blood form clots to stop bleeding. Injections of factor IX are used to treat hemophilia B, which is sometimes called Christmas disease. This is a condition in which the body does not make enough factor IX. If you do not have enough factor IX and you become injured, your blood will not form clots as it should, and you may bleed into and damage your muscles and joints.

Injections of one form of factor IX, called factor IX complex, also are used to treat certain people with hemophilia A. In hemophilia A, sometimes called classical hemophilia, the body does not make enough factor VIII, and, just as in hemophilia B, the blood cannot form clots as it should. Injections of factor IX complex may be used in patients in whom the medicine used to treat hemophilia A is no longer effective. Injections of factor IX complex also may be used for other conditions as determined by your doctor.

The factor IX product that your doctor will give you is obtained naturally from human blood or artificially by a man-made process. Factor IX obtained from human blood has been treated and is not likely to contain harmful viruses such as hepatitis B virus, hepatitis C (non-A, non-B) virus, or human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS). The man-made factor IX product does not contain these viruses.

Factor IX is available only with your doctor’s prescription.

Other uses (PubMed Health)

How To Use

Injectable

Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

A nurse or other health provider will give you this medicine.

You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

Use a new needle and syringe each time you inject your medicine.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Missed dose: Ask your doctor or pharmacist for instructions, if you need to use this medicine on a schedule.

Each brand of medicine has different instructions for how to store it. Follow the directions for your brand. Ask your doctor or pharmacist if you have any questions. Do not use this medicine after the expiration date.

Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

When Not To Use

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to coagulation factor (recombinant) or hamster proteins, or if you have disseminated intravascular coagulation (DIC).

Warnings

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or liver disease.

This medicine may cause the following problems:

Increased risk for blood clots Kidney problems

Tell your doctor if this medicine does not prevent or stop bleeding as expected.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible side effects

Summary More details

Call your doctor right away if you notice any of these side effects:

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Change in how much or how often you urinate

Chest pain, trouble breathing, coughing up blood

Lightheadedness, dizziness, fainting

Numbness or weakness in your arm or leg, or on one side of your body

Pain in your lower leg (calf)

Sudden or severe headache, problems with vision, speech, or walking

Unexplained bleeding

If you notice these less serious side effects, talk with your doctor:

Headache

Pain, itching, burning, redness, swelling, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

More side effects of this drug

Brand names include

Alphanine SD, Alprolix, Bebulin, Bebulin VH, Benefix, Ixinity, Mononine, Profilnine SD, Proplex T, Rixubis

There may be other brand names for this medicine.