Tacrolimus (On the skin)
Antipsoriatic (About this – PubMed Health)
Uses of This Medicine
Tacrolimus topical is used on the skin to treat moderate to severe atopic dermatitis in patients who have received other medicines that have not worked well. Atopic dermatitis is a skin condition where there is itching, redness, and inflammation, much like an allergic reaction. Tacrolimus helps to suppress these symptoms which are reactions caused by the body’s immune system.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Your doctor will tell you how much medicine to use. Do not use more than directed.
Wash your hands before you apply this medicine. If you are not treating a skin rash on your hands, then you should also wash your hands with soap and water after you apply the medicine. However, do not wash your hands after if you are treating a rash on your hands. Do not bathe or swim immediately after applying this medicine. This could wash the medicine off.
Apply a thin layer of the medicine to the affected area. Rub it in gently. Apply the medicine 2 times daily, at least 12 hours apart, unless your doctor tells you otherwise. Apply just enough to cover the area. Only apply this medicine to areas where eczema appears.
You may apply a moisturizer to your skin after you apply the medicine, if your doctor approves it.
Do not cover the treated area with a bandage unless directed by your doctor.
This medicine is not for long-term use. Use the medicine only until your skin symptoms are gone. If the eczema comes back, you may start using the medicine again if your doctor approves. You must take breaks in between treatments.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
If a dose is missed:
Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not leave the ointment in the car in cold or hot weather. Make sure that the tube is tightly closed.
Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using cimetidine (Tagamet®), tacrolimus capsules (Prograf®), an antibiotic such as erythromycin (Ery-tab®), or an antifungal medicine such as fluconazole, ketoconazole, itraconazole, Diflucan®, Nizoral®, or Sporanox®. Tell your doctor if you are also using blood pressure medicines such as diltiazem, nifedipine, verapamil, Adalat®, Calan®, Cardizem®, Lotrel®, Plendil®, or Procardia®.
Make sure your doctor knows if you are receiving any type of UV (ultraviolet) light treatment or phototherapy.
Alcohol may cause flushing or redness in your face.
When Not To Use
You should not use this medicine if you have had an allergic reaction to tacrolimus. Do not use this medicine on a child younger than 2 years of age.
Make sure your doctor knows if you are pregnant or breastfeeding. Tell your doctor if you have kidney problems, mononucleosis (mono), weakened immune system, or a history of an organ transplant. Tell your doctor if you have a skin infection, skin cancer, lymphoma, or skin absorption problems (such as lamellar ichthyosis, graft versus host disease, erythroderma, or Netherton syndrome).
This medicine should not be used continuously for a long time. When the rash is gone, stop using the medicine. If your doctors says it is okay, you may start using the medicine again if the rash comes back, but you should allow time in between treatments.
Call your doctor if your symptoms do not improve or if they get worse. Call your doctor if your symptoms do not improve within 6 weeks.
Do not use this medicine to treat a skin problem your doctor has not examined.
This medicine may increase your chances of catching chicken pox, shingles, or herpes virus (including cold sores). Avoid people who have these infections. Call your doctor if you think you have been exposed to one of these illnesses.
This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds. Limit your time in the sun as much as possible. Cover the treated areas of your skin with loose clothing if you must be outside.
This medicine may make you sick if it is not used correctly. Call a doctor or poison control center right away if you accidentally swallow this medicine.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
New skin problems, including chicken pox, shingles, or cold sores
If you notice these less serious side effects, talk with your doctor:
Mild burning, stinging, tingling, redness, or itching when the medicine is applied
Extra sensitive skin
Swollen or infected hair follicles
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.