Omeprazole (By mouth)
Uses of This Medicine
Omeprazole is used to treat certain conditions where there is too much acid in the stomach. It is used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus. Sometimes omeprazole is used in combination with antibiotics (eg, amoxicillin, clarithromycin) to treat ulcers associated with infection caused by the H. pylori bacteria (germ).
Omeprazole is also used to treat Zollinger-Ellison syndrome, a condition where the stomach produces too much acid.
Omeprazole is also used to treat dyspepsia, a condition that causes sour stomach, belching, heart burn, or indigestion.
Omeprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.
This medicine is available both over-the-counter (OTC) and with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Delayed Release Capsule, Packet, Powder for Suspension, Delayed Release Tablet
Your doctor will tell you how much medicine to use. Do not use more than directed.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Follow the instructions on the medicine label if you are using this medicine without a prescription. If you are using the over-the-counter medicine, do not take it for more than 14 days or use the treatment more often than every 4 months unless your doctor tells you to.
Take this medicine at least 1 hour before a meal and for the full time of treatment, even if you begin to feel better after a few days.
Capsule or tablet:Swallow whole. Do not crush or chew it. If you cannot swallow the capsule, you may open it and pour the medicine into a small amount of applesauce. Stir this mixture well and swallow it without chewing. To help make sure you get the full dose, drink a full glass of water.
Oral packet:Mix the contents of a 2.5-milligram (mg) packet with 5 milliliters (mL) of water or mix the contents of a 10-mg packet with 15 mL of water. Do not use other liquids or food. Stir well. Let the mixture thicken for 2 to 3 minutes. Stir again and drink the medicine within 30 minutes. If there is any medicine left, add more water, stir, and drink immediately. To prepare the oral packet for a feeding tube: Add 5 mL of water to a catheter-tipped syringe. Then add the contents of a 2.5-mg packet (or use 15 mL of water for the 10-mg packet). Shake the syringe right away. Let the mixture thicken for 2 to 3 minutes. Shake the syringe once more. Give the medicine through the tube within 30 minutes. Refill the syringe with an equal amount of water and shake it. Use the water to flush the tube. This helps make sure all the medicine is given.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines can affect how omeprazole works. Tell your doctor if you are using any of the following:Ampicillin, atazanavir, cilostazol, clarithromycin, clopidogrel, cyclosporine, digoxin, disulfiram, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, phenytoin, rifampin, saquinavir, St John’s wort, tacrolimus, voriconazole Benzodiazepine medicine (such as diazepam) Blood thinner (such as warfarin) Diuretic (water pill) Iron supplements
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to omeprazole or similar medicines.
This medicine can cause the following problems:Kidney problems Low vitamin B12 or magnesium levels Increased risk of broken bones in the hip, wrist, or spine
This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Severe diarrhea, stomach cramps, fever
If you notice these less serious side effects, talk with your doctor:
Mild diarrhea or stomach pain
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
First – Omeprazole, First-Omeprazole, Good Neighbor Pharmacy Omeprazole, Good Sense Omeprazole, Leader Omeprazole, Omeclamox-Pak, Prilosec, Prilosec OTC, Quality Choice Omeprazole Magnesium, Rite Aid Omeprazole, Sunmark Omeprazole, TopCare Omeprazole
There may be other brand names for this medicine.