Ziprasidone (By injection)
zi-PRAS-i-done
Treats agitation in patients with schizophrenia.
Drug classes
Antipsychotic (About this – PubMed Health)
Uses
Uses of This Medicine
Ziprasidone injection is used to treat agitation that occurs with schizophrenia. It should not be used to treat behavioral problems in elderly patients who have dementia. Ziprasidone works by changing some of the chemicals in the brain that cause schizophrenia.
This medicine is to be given only by or under the direct supervision of your doctor.
Other uses (PubMed Health)
How To Use
Injectable
Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
A nurse or other health provider will give you this medicine.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
You should not receive this medicine together with amiodarone, arsenic trioxide, chlorpromazine, disopyramide, dofetilide, dolasetron mesylate, droperidol, gatifloxacin, halofantrine, levomethadyl acetate, mefloquine, mesoridazine, moxifloxacin, pentamidine, pimozide, probucol, procainamide, quinidine, sotalol, sparfloxacin, tacrolimus, or thioridazine.
Some foods and medicines can affect how ziprasidone works. Tell your doctor if you are using any of the following:
Carbamazepine, ketoconazole, levodopa Blood pressure medicines Diuretic (water pill)When Not To Use
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to ziprasidone, or if you have a history of QT prolongation (heart rhythm problem) or had a recent heart attack.
Warnings
Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, blood or bone marrow problems, diabetes, high cholesterol, or a history of seizures or breast cancer. Tell your doctor if you have heart rhythm problems or any heart or blood vessel problems, including low blood pressure, heart failure, or history of a heart attack.
This medicine may cause the following problems:
Heart rhythm problems Neuroleptic malignant syndrome (possibly life-threatening neurological disorder) Drug reaction with eosinophilia and systemic symptoms (DRESS), which can damage organs such as the liver, kidney, or heart Serious skin reactions Tardive dyskinesia (trouble controlling muscle movements)This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.
You may get overheated more easily while you are using this medicine. Use caution when you exercise strenuously or are outside in hot weather. Drink plenty of water to stay hydrated.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, red skin rash
Chills, cough, sore throat, and body aches
Fast, slow, pounding, or uneven heartbeat
Fever, skin rash, or swollen glands in your armpits, neck, or groin
Fever, sweating, confusion, muscle stiffness, seizures
Increased thirst, hunger, or urination
Lightheadedness, dizziness, or fainting
Painful, prolonged erection of your penis
Twitching or muscle movements you cannot control (especially in your face, tongue, or jaw)
Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
Pain where the shot was given
Sleepiness, tiredness
Weight gain
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Geodon
There may be other brand names for this medicine.
