Factor XIII (By injection)
Hemostatic (About this – PubMed Health)
Uses of This Medicine
Factor XIII is a protein that is produced naturally in the body. Corifact™ or Tretten® is a man-made protein produced to replicate the naturally occurring factor XIII in the body. It is used to stop bleeding by helping the blood to clot.
This medicine is to be given only by or under the supervision of your doctor or other health care professional.
Other uses (PubMed Health)
How To Use
Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
A nurse or other health provider will give you this medicine.
This medicine is usually given about once a month, depending on your recent blood test results.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Some medicines can affect how factor XIII works. Tell your doctor if you are also using factor VIIa.
When Not To Use
This medicine is not right for everyone. You should not receive this medicine if you have had an allergic reaction to a coagulation factor or to products made from human blood.
This medicine may cause the following problems:Blood clots
Corifact® is made from donated human blood. There is a very small risk that it could contain a virus, although all medicines and donors are checked for viruses.
Tell your doctor if this medicine does not prevent or stop bleeding as expected.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Pain in your lower leg (calf)
Unexplained bleeding, severe bruises that you cannot explain
If you notice these less serious side effects, talk with your doctor:
Pain under your skin where the needle is placed
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
There may be other brand names for this medicine.