Adapalene/Benzoyl Peroxide (On the skin)
a-DAP-a-leen, BEN-zoe-il per-OX-ide
Antiacne (About this – PubMed Health)
Uses of This Medicine
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Your doctor will tell you how much medicine to use. Do not use more than directed. Extra medicine will not make it work faster and may cause red, peeling, or irritated skin.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Before you apply this medicine, wash your skin with water and a mild soap. Rinse well and pat dry.
Apply a thin layer of the medicine to the affected area. Rub it in gently.
Missed dose: Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Do not use any other medicines on the treated skin areas without asking your doctor. Do not use any skin care products that can dry or irritate your skin. These include rough skin cleansers, hair removal products, soaps or cosmetics that cause dryness, or products that contain alcohol, astringents, spices, or lime.
When Not To Use
This medicine is not right for everyone. Do not use it if you had an allergic reaction to adapalene or to benzoyl peroxide.
Tell your doctor if you are pregnant or breastfeeding.
This medicine may make your skin more sensitive to sunlight, wind, and cold weather. Use sunscreen when you are outdoors, and wear protective clothing, such as a hat. Do not use a sunlamp or tanning bed.
Use a moisturizer as needed if your skin becomes irritated.
Do not use waxing as a hair removal method on skin areas treated with this medicine.
Allow this medicine to dry completely before you get dressed. This medicine may cause bleaching of clothes or hair.
Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
You may need to use this medicine for several weeks or months before your skin starts to look better.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Blistering, burning, crusting, dryness, or flaking of the skin
Severe redness or swelling of the skin
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Epiduo, Epiduo Forte
There may be other brand names for this medicine.