Silver Sulfadiazine (On the skin)
Antibacterial (About this – PubMed Health)
Uses of This Medicine
Silver sulfadiazine cream is used to prevent and treat wound infections in patients with second- and third-degree burns. Patients with severe burns or burns over a large area of the body must be treated in a hospital.
This medicine is available only with your doctor’s prescription.
Other uses (PubMed Health)
How To Use
Your doctor will tell you how much medicine to use. Do not use more than directed.
Before using the cream, clean off any dead skin or scabbing from the burn wound.
Wear sterile gloves to apply this medicine.
Spread a thin layer of the cream over the wound. You may then cover the wound with a bandage if needed.
Keep the wound area clean and covered with the medicine at all times.
If the cream washes off during a bath or other activity, clean the wound again and put on more cream.
To help clear up your skin or burn infection completely, keep using this medicine for the full time of treatment. You should keep using this medicine until the burned area has healed or is ready for skin grafting.
If a dose is missed:
Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.
Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Drugs and Foods to Avoid
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Make sure your doctor knows if you are also using cimetidine (Tagamet®).
Do not put cosmetics or skin care products on the treated skin.
When Not To Use
Do not use this medicine if you have had an allergic reaction to silver sulfadiazine. Do not use this medicine on pregnant women approaching or near giving birth, premature babies, or newborn babies 2 months of age and younger.
This medicine is a sulfa drug (sulfonamide). Rarely, this topical cream might cause some of the side effects seen with oral sulfa drugs. This includes allergic reactions. Check with your doctor right away if you have a blistering, peeling, red skin rash or other severe symptoms (such as unusual bleeding, bruising, or weakness).
If your burn wounds do not heal or if they become worse, call your doctor.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Do not use this medicine to treat a skin problem your doctor has not examined.
Possible side effects
Summary More details
Call your doctor right away if you notice any of these side effects:
Blistering, peeling, or red skin rash
Change in how much or how often you urinate
Unusual bleeding, bruising, weakness
If you notice these less serious side effects, talk with your doctor:
Changes in skin color
Skin discomfort when in sunlight
If you notice other side effects that you think are caused by this medicine, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
More side effects of this drug
Brand names include
Flamazine, SSD AF, Silvadene, Ssd, Thermazene
There may be other brand names for this medicine.